ACHIEVEMENTS

PUBLICATION

2025

  • Asrani K, Amaral A, Woo J, Abadchi SN, Vidotto T, Imada E, Skaist A, Feng K, Liu HB, Kasbe M, Satou Y, Baba M, Oike Y, Outeda P, Watnick T, Rosenberg
    AZ, Schmidt LS, Linehan WM, Argani P, Lotan TL. Nature Communications, 16(1),
    8822    , doi: 10.1038/s41467-025-63885-2.
  • Reda O, Satou Y.  HIV-1潜伏感染の多層的ダイナミクスを可視化するHIV-Tockyシステム ウイルス,
    2025, 75巻, 1号, 35-38.     doi:10.2222/jsv.75.35
  • Katsuya H, Satou Y, Kimura S. Advances in clonality
    analysis of human T-cell leukemia virus type 1-infected cells: from Southern blotting to high-throughput
    sequencing. Journal of
    Clinical and Experimental Hematopathology    . 2025 Sep 28;65(3):167-173.     doi:
    10.3960/jslrt.25035.  Review article.
  • Nakamura H, Watanabe T, Sato A, Kawaguchi A, Uchimaru K, Satou
    Y    , Sueoka E. A comprehensive assessment using multiple factors based on HAS-Flow analysis
    predicts ATL development and progression. Scientific Reports. 2025, 15,
    26618. doi: 10.1038/s41598-025-10822-4
  • Jahan MI, Inenaga T, Makimoto S, Hossain MB, Matsuoka Y, Sithi
    SN    , Rajib SA, Ansori ANM, Sugata
    K    , Imakawa K, Kobayashi T, Satou Y. Circulating
    Cell-Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis. Microbiol Immunol.
    2025 Jul 7. doi: 10.1111/1348-0421.13231. Online ahead of print.
  • Irie N, Takeda N, Satou Y, Araki K, Ono M. Machine
    learning-assisted decoding of temporal transcriptional dynamics via fluorescent timer. Nature Communications, 2025,
    16, 5720, doi: 10.1038/s41467-025-61279-y.
  • Sugata K, Rahman
    A    , Niimura K, Monde K, Ueno Takaharu, Rajib SA, Takatori M, Sakhor W, Hossain
    MB    , Sithi SN, Jahan MI, Matsuda K, Ueda M, Yamano Y, Ikeda T, Ueno
    Takamasa, Tsuchiya K, Tanaka Y, Tokunaga M, Maeda K, Utsunomiya A, Okuma K, Ono M, Satou Y. Intragenic viral silencer element regulates HTLV-1
    latency via RUNX complex recruitment.  Nature Microbiology,
    doi: 10.1038/s41564-025-02006-7    .
  • Pineda MV, Miyazato P, Distefano M, Tan BJY, Bouzas MB, Satou
    Y    , Mangano A.
    First Characterization HTLV-1 Complete Genomes from Asymptomatic and Symptomatic Argentinean Patients.
    AIDS Res Hum Retroviruses.
    2025. doi: 10.1089/aid.2024.0068.     Online ahead of print.
  • Funasaki S, Miyamura Y, Kamei S, Rahman A, Yamazaki M,
    Usuki S, Yasunaga K, Satou Y, Ohguchi H, Minami T.
    Protocol for transcriptomic and epigenomic analyses of tip-like endothelial cells using scRNA-seq and
    ChIP-seq.
    STAR
    Protocol    . 2025, 6(1), 103326    . doi: 10.1016/j.xpro.2024.103326
  • Nishizawa H, Funasaki S, Ma W, Kubota Y, Watanabe K, Arima Y, Kuroda S, Ito T, Furuya M, Motoshima T,
    Nishiyama A, Mehanna S, Satou Y, Hasumi H, Jikuya R,
    Makiyama K, Tamura T, Oike Y, Tanaka Y, Suda T, Schmidt LS, Linehan WM, Baba M, Kamba T.
    HIF1α Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a
    Metabolic Shift Toward Fatty Acid Synthesis.
    Genes to Cells. 2025,
    30(1), e13195    . doi: 10.1111/gtc.13195
  • Morodomi S, Hirosue A, Rahman A, Nohata K, Matsuo M, Reda O, Alam Rajib
    S    , Saito H, Takeda H, Yoshida R, Nakamoto M, Hirayama M, Kawahara K, Takatori M, Orita Y,
    Nakayama H, Satou Y.
    Robust HPV-16 Detection Workflow for Formalin-Fixed Cancer Tissue and Its Application for Oral Squamous Cell
    Carcinoma.
    Cancer Medicine. 2025,
    14(4), e70544    . doi: 10.1002/cam4.70544.
  • Hossain MB, Tan BJY, Satou Y.
    Viral oncogenesis of δ-retroviruses, HTLV-1 and BLV, and recent advances in its diagnosis.
    Virology.
    2025, 605, 110461    . doi: 10.1016/j.virol.2025.110461.

2024

  • Takahama S, Washizaki A, Okamura T, Kitamura S, Nogimori T, Satou
    Y    , Yasutomi Y, Yoshinaga T, Yamamoto T.
    The quality of SIV-specific fCD8 T cells limits SIV RNA production in Tfh cells during antiretroviral
    therapy.

    Journal of Viology    . 2024, e0081224    . doi: 10.1128/jvi.00812-24
  • Wang K, Nagai H, Rajib SA, Satou Y, Ueno M.
    Decreased mitochondrial translation confers 3,3′-Diindolylmethane resistance to Schizosaccharomyces
    pombe.
    Biochemical
    and Biophysical Research Communication    . 2024, 736(3), 150864    .
    doi:10.1016/j.bbrc.2024.150864
  • Tang J, Funasaki S, Nishizawa H, Kuroda S, Motoshima T, Wu C, Mawas AS, Satou Y, Arima Y, Hasumi H, Jikuya R, Makiyama K, Oike Y,
    Tanaka Y, Baba M, Kamba T.
    ARID2 Deficiency Enhances Tumor Progression via ERBB3 Signaling in TFE3-Rearranged Renal Cell Carcinoma.
    Current issues in molecular biology.
    2024, 46, 13675    . doi:10.3390/cimb46120817
  • Kobayashi T, Makimoto S, Ohnuki N, Hossain MB, Jahan MI, Matsuo M, Imakawa K, Satou Y.
    A rapid and simple clonality assay for bovine leukemia virus-infected cells by amplified fragment length
    polymorphism (AFLP) analysis.
    Microbiology
    Spectrum    . 2024, 13(1),e0171424    . doi: 10.1128/spectrum.01714-24
  • Kimura M, Umekita K, Iwao C, Kawano K, Hashikura Y, Hashiba Y, Hidaka T, Sugata K, Satou
    Y    , Miyazaki T.
    Antiviral immune response against HTLV-1 invalidates T-SPOT.TB® results in patients with HTLV-1-positive
    rheumatic diseases.
    Frontiers
    in Immunology    . 2024, 15, 1480506    . doi:10.3389/fimmu.2024.1480506
  • Thinyakul C, Sakamoto Y, Shimoda M, Liu Y, Thongchot S, Reda
    O    , Nita A, Sakamula R, Sampattavanich S, Maeda A, Chunthaboon P, Nduru D, Niimura M, Kanamori Y,
    Thuwajit P, Nakayama KI, Guan KL, Satou Y, Thuwajit C,
    Moroishi T.
    Hippo pathway in cancer cells modulates tumor microenvironment by inducing immunosuppressive NCAM1+αSMA+
    fibroblasts.
    Communications Biology. 2024,
    7, 1343    . doi:10.1038/s42003-024-07041-4
  • Sugata K, Takatori M, Reda O, Tan BJY, Tokunaga M, Sato T, Ueda M, Yamano Y,
    Utsunomiya A, Satou Y.
    Effect of Viral Antigen Mismatch on Antiviral T-Cell Response and Immunotherapeutic Efficacy Against Adult
    T-Cell Leukemia/Lymphoma.
    The
    Journal of Infectious Diseases.     2024, jiae457    . doi:10.1093/infdis/jiae457
  • White E, Papagno L, Samri A, Sugata K, Hejblum B, Henry AR,
    Rogan DC, Darko S, Recordon-Pinson P, Dudoit Y, Llewellyn-Lacey S, Chakrabarti LA, Buseyne F, Migueles SA,
    Price DA, Andreola MA, Satou Y, Thiebaut R, Katlama C,
    Autran B, Douek DC, Appay V.
    Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against
    HIV-1.
    Nature Immunology.
    25(9):1555-1564    . doi: 10.1038/s41590-024-01931-9.
  • Nyame P, Togami A, Yoshida T, Masunaga T, Begum MM, Terasawa H, Monde N, Tahara Y, Tanaka R, Tanaka Y,
    Appiah-Kubi J, Amesimeku WO, Hossain MJ, Otsuka M, Yoshimura K, Ikeda T, Sawa T, Satou Y, Fujita M, Maeda Y, Tateishi H, Monde K.
    A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24.
    J Biol Chem. Online ahead of
    print. 107701.     doi: 10.1016/j.jbc.2024.107701.
  • Hossain B, Uchiyama Y, Rajib SA, Rahman
    A    , Takatori M, Tan BJY, Sugata K, Nagashima M,
    Kawakami M, Ito H, Kumagai R, Sadamasu K, Ogi Y, Kawaguchi T, Tamura T, Fukuhara T, Ono M, Yoshimura K,
    Satou Y. A micro-disc-based multiplex method for monitoring
    emerging SARS-CoV-2 variants using the molecular diagnostic tool Intelli-OVI.
    Communications medicine. 2024,
    4(161)    , doi: 10.1038/s43856-024-00582-z
  • Begum MM, Bokani A, Rajib SA, Soleimanpour M, Maeda Y,
    Yoshimura K, Satou Y, Ebrahimi D, Ikeda T. Potential Role
    of APOBEC3 Family Proteins in SARS-CoV-2 Replication.
    Viruses. 16(7):1141. doi:
    10.3390/v16071141.
  • Omnia R, Monde K, Sugata K, Rahman
    A    , Sakhor W, Rajib SA, Sithi
    SN    , Tan BJY, Niimura K, Motozono C, Maeda K, Ono
    M, Takeuchi H, Satou Y. HIV-Tocky system to visualize
    proviral expression dynamics.
    Communications Biology, 7:
    344, 2024    . doi: 10.1038/s42003-024-06025-8.
  • Ono M and Satou Y. Spectrum of Treg and Self-Reactive T
    cells: Single Cell Perspectives from Old Friend HTLV-1.
    Discovery
    Immunology     3(1):kyae006    , 2024  doi: 10.1093/discim/kyae006.
  • Miyamura Y, Kamei S, Matsuo M, Usuki S, Uemura A, Satou Y,
    Ohguchi H, and Minami T.FOXO1 stimulates tip cell-enriched gene expression in endothelial cells.
    iScience, 2024, 27(3), 109161. doi: 10.1016/j.isci.2024.109161.
  • Konno Y, Uriu K, Chikata T, Takada T, Kurita JI, Ueda MT, Islam S, Yang Tan BJ, Ito J, Aso H, Kumata R,
    Williamson C, Iwami S, Takiguchi M, Nishimura Y, Morita E, Satou
    Y    , Nakagawa S, Koyanagi Y, Sato K.Two-step evolution of HIV-1 budding system leading to pandemic
    in the human population.
    Cell Rep. 2024, 43(2),113697,doi: 10.1016/j.celrep.2024.113697

2023

  • Tomita Y, Sakata S, Imamura K, Iyama S, Jodai T, Saruwatari K, Hamada S, Akaike K, Anai M, Fukusima K,
    Takaki A, Tsukamoto H, Goto Y, Motozono C, Sugata K, Satou
    Y    , Ueno T, Ikeda T, Sakagami T. Association of Clostridium butyricum therapy using the live
    bacterial product CBM588 with the survival of patients with lung cancer receiving chemoimmunotherapy
    combination.
    Cancer. 2023, 16(1), 47, doi: 10.3390/cancers16010047.
  • Nakahata S, Enriquez-Vera D, M. Jahan I, Sugata K, Satou Y. Understanding the Immunopathology of
    HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review.Biomolecules,
    2023, 13(10), 1543, doi: 10.3390/biom13101543.
  • Matsuda K, Tan BJY, Tsuchiya K, Rajib SA, Satou Y and Maeda K.Assessing the effects of antiretroviral
    therapy-latency-reversing agent combination therapy on eradicating replication-competent HIV provirus in a
    Jurkat cell culture model. STAR Protocol. 2023, 4(4), 102547,doi:
    10.1016/j.xpro.2023.102547.
  • Katsuya H, Nakamura H, Maeda A, Ishii K, Nagaie T, Sano H, Sano H, Itamura H, Okamoto S, Ando T, Watanabe T,
    Uchimaru K, Satou Y, Sueoka E, Kimura S. HTLV-1 cell-free
    DNA in plasma as a potential biomarker in HTLV-1 carriers and adult T-cell leukemia-lymphoma.
    eJHaem. 2023, 4(3), 733-737, doi: 10.1002/jha2.725.
  • Akiyama T, Yasuda T, Uchihara T, Yasuda-Yoshihara N, Tan
    BJY    , Yonemura A, Semba T, Yamasaki J, Komohara Y, Ohnishi K, Wei F, Fu L, Zhang J, Kitamura F,
    Yamashita K, Eto K, Iwagami S, Tsukamoto H, Umemoto T, Masuda M, Nagano O, Satou Y, Saya H, Tan P, Baba H, Ishimoto T. Stromal
    Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic
    Tumors. CANCER
    RESEARCH.     83 (5), 753–770    , 10.1158/0008-5472.CAN-22-1890
  • Hossain B, Kobayashi T, Makimoto S, Matsuo M, Nishikaku K, Tan B, Rahman A, Rajib SA, Sugata K, Ohnuki N,
    Saito M, Inenaga T, Imakawa K, Satou Y. Clone Dynamics and Its Application for the Diagnosis of Enzootic
    Bovine Leukosis. Journal of
    Virology    . doi:https://doi.org/10.1128/jvi.01542-22

2022

  • Tan B, Sugata K, Ono M and Satou Y. HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the
    host immune system. Frontiers in Immunology. 13:991928. doi: 10.3389/fimmu.2022.991928
  • Tan B, Ono M, Satou Y. Single-cell transcriptome analysis of Treg, In: Ono
    M. (eds) Regulatory T Cells. pp259-278.
  • Maksimova V, Smith S, Seth J, Phelps C, Niewiesk S, Satou
    Y    , Green P, Panfil A. Identification and characterization of a novel enhancer in the HTLV-1
    proviral genome. Frontiers in Immunology. 13:954077. doi: 10.3389/fimmu.2022.954077
  • Matsuo M, Ueno T, Monde K, Sugata K, Tan
    B    , Rahman A, Miyazato P, Uchiyama K, Islam S,
    Katsuya H, Nakajima S, Tokunaga M, Nosaka K, Hata H, Utsunomiya A, Fujisawa,  Satou Y. Identification and characterization of a novel
    enhancer in the HTLV-1 proviral genome. Nature Communications. 13,2405,
    2022    . doi:10.1038/s41467-022-30029-9
  • Monde K, Satou Y, Goto M, Uchiyama Y, Ito J, Kaitsuka T, Terasawa H, Monde N, Yamaga S, Matsusako T,
    Wei FY, Inoue I, Tomizawa K, Ono A, Era T, Sawa T, Maeda Y. Movements of Ancient Human Endogenous
    Retroviruses Detected in SOX2-Expressing Cells., J Virol. in press
  • Rajib SA, Ogi Y, Hossain MB, Tanaka E, Kawaguchi T, Satou Y. A SARS-CoV-2 Delta variant
    containing mutation in the probe binding region used for qRT-PCR test in Japan exhibited atypical PCR
    amplification and might induce false negative result Journal of Infection and Chemotherapy in press
  • Katsuya H, Cook L, Rowan AG, Melamed A, Turpin J, Ito J, Islam S, Miyazato P, Tan B, Matsuo M,
    Miyakawa T, Nakata H, Matsushita S, Taylor GP, Bangham CRM, Kimura S, Satou Y. Clonality of HIV-1 and
    HTLV-1 infected cells in naturally coinfected individuals. The Journal of Infectious Diseases 225(2), 317-326, 2022.

2021

  • Tan B, Sugata K, Reda O, Matsuo M, Uchiyama K, Miyazato P, Hahaut V, Yamagishi
    M, Uchimaru K, Suzuki Y, Ueno T, Suzushima H, Katsuya H, Tokunaga M, Uchiyama Y, Nakamura H, Sueoka E,
    Utsunomiya A, Ono M, Satou Y. HTLV-1 infection promotes excessive T cell activation and
    transformation into adult T cell leukemia/lymphoma. The Journal of Clinical Investigation 131(24),
    e150472, 2021.
  • Matsuda K, Islam S, Takada T, Tsuchiya K, Tan B, Hattori S, Katsuya H, Kitagawa K, Kim
    K,Matsuo M, Sugata K, Delino N, Gatanaga H, Yoshimura K, Matsushita S, Mitsuya H, Iwami S,
    Satou Y, Maeda K. A widely distributed HIV-1 provirus elimination assay to evaluate latency-reversing
    agents in vitro. Cell Reports Methods 1(8), 100122, 2021.
  • Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa
    JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.
    M-Sec induced by HTLV-1 mediates an efficient viral transmission. PLoS Pathogens 17:e1010126, 2021.
  • Ohnuki N, Kobayashi T, Matsuo M, Nishikaku K, Kusama K, Torii Y, Inagaki Y, Hori M, Imakawa K,
    Satou Y. A target enrichment high throughput sequencing system for characterization of BLV whole
    genome sequence, integration sites, clonality and host SNP. Scientific Reports 11(1), 4521, 2021.
  • Sugata K,Matsunaga Y, Yamashita Y, Nakatsugawa M, Guo T, Halabelian L, Ohashi Y, Saso K, Rahman M,
    Anczurowski M, Wang C, Murata K, Saijo H, Kagoya Y, Ly D, Burt B, Butler M, Mak T, Hirano N.
    Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells. Nature Biotechnology doi: 10.1038/s41587-021-00836-4, 2021.

2020

2019

  • Miyazato P, Matsuo M, Tan BJY, Tokunaga M, Katsuya H, Islam S, Ito J, Murakawa Y, Satou Y. HTLV-1 contains a high CG dinucleotide content and is susceptible to
    the host antiviral protein ZAP. Retrovirology, 16(1):38, doi:
    10.1186/s12977-019-0500-3,2019.
  • Katsuya H, Islam S, Tan BJY, Ito J, Miyazato P, Matsuo M, Inada Y, Iwase SC, Uchiyama Y, Hata H, Sato T,
    Yagishita N, Araya N, Ueno T, Nosaka K, Tokunaga M, Yamagishi M, Watanabe T, Uchimaru K, Fujisawa JI,
    Utsunomiya A, Yamano Y, Satou Y. The Nature of the HTLV-1 Provirus in
    Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach. Cell
    Reports    , 29(3):724-735.e4, doi: 10.1016/j.celrep.2019.09.016, 2019.
  • Iwase S, Miyazato P, Katsuya H, Islam S, Tan BJY, Ito J, Matsuo M, Takeuchi H, Ishida T, Matsuda K, Maeda K
    and Satou Y. HIV-1 DNA-capture-seq is a useful tool for the comprehensive
    characterization of HIV-1 provirus.
    Scientific Reports, 29(3):724-735.e4, doi: 10.1016/j.celrep.2019.09.016, 2019.
  • Baba M, Furuya M, Motoshima T, Martin L, Funasaki S, Wenjuan M, Hong-Wei S, Hasumi H, Ying H, Kato I,
    Kadomatsu T, Satou Y, Nicole MN, Baktiar OK, Lilia I, Joseph DK, Luh AWK,
    Hasumi Y, Sugiyama A,
    Kurahashi R, Nishimoto K, Oyama M, Nagashima Y, Kuroda N, Araki K, Eto M, Yao M, Kamba T, Suda T,
    Oike Y, Laura SS and W. Marston L. TFE3 Xp11.2 translocation renal cell carcinoma mouse model reveals novel
    therapeutic targets and identifies GPNMB as a diagnostic marker for human disease.
    Molecular Cancer Research, 17(8):1613-1626, doi: 10.1158/1541-7786.MCR-18-1235,
    2019.
  • 松尾美沙希、宮里パオラ、佐藤賢文
    「HTLV-1感染細胞クローン選択におけるウイルス組み込み部位の意義
    〜レトロウイルスHTLV-1とヒトゲノムの相互作用に関する最近の話題〜」     ウイルス　第69巻 第1号　2019年
  • 佐藤賢文「HIV-1ウイルスリザーバの成立・維持の仕組み」 日本エイズ学会誌　21:167-172　2019年

2018

  • Miura M, Miyazato P, Satou Y, Tanaka Y, Bangham CRM. Spontaneous HTLV-1
    transcription is accompanied by distinct epigenetic changes in the 5′ and 3′ long terminal repeats.
    Wellcome Open Research, 3:105, doi: 10.12688/wellcomeopenres.14741.2. eCollection
    2018, 2018.
  • Katsuya H, Cook LBM, Rowan AG, Satou Y, Taylor GP, Bangham CRM.
    Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell
    leukemia-lymphoma.
    Biomarker Research, 6:24, doi: 10.1186/s40364-018-0138-7, 2018.
  • Stanoeva K, Konig A, Fukuda A, Kawanami Y, Kuwata T,
    Satou Y, Matsushita S. Total HIV-1 DNA dynamics and influencing factors in long-term ART-treated
    Japanese adults: retrospective longitudinal analysis.
    Journal of Acquired Immune Deficiency Syndromes, 78(2):239-247, doi:
    10.1097/QAI.0000000000001662, 2018.

2017

  • Satou Y, Katsuya H, Fukuda A, Misawa N, Ito J, Uchiyama Y,
    Miyazato P,
    Islam S, Fassati A, Melamed A, Bangham CRM, Koyanagi Y, Sato K. Dynamics and mechanisms of clonal expansion
    of HIV-1-infected cells in a humanized mouse model.
    Scientific Reports, 7(1):6913, doi: 10.1038/s41598-017-07307-4, 2017.

2016

  • Miyazato P, Katsuya H,
    Fukuda A, Uchiyama Y, Matsuo M, Tokunaga M, Hino S , Nakao M, Satou Y.
    Application of targeted enrichment to next-generation sequencing of retroviruses integrated into the host
    human genome. Scientific Reports, 6:28324, doi: 10.1038/srep28324, 2016.
  • Miyazato P, Matsuo M, Katsuya H, Satou Y. Transcriptional and Epigenetic
    Regulatory Mechanisms affecting HTLV-1 provirus. Viruses, 8(6):171, doi:
    10.3390/v8060171, 2016.
  • Satou Y, Miyazato P, Ishihara K, Yaguchi H, Melamed A, Miura M,
    Fukuda A, Nosaka K, Watanabe T, Rowan A, Nakao M, Bangham C. The retrovirus HTLV-1 inserts an ectopic
    CTCF-binding site into the human genome. Proceedings of the National Academy of Sciences of the
    United States of America    , 113(11):3054-9, doi: 10.1073/pnas.1423199113, 2016.
    [熊大HP][EurekAlert!HP][HTLV-1学会]

2014

  • Zhao T, Satou Y, Matsuoka M. Development of T cell lymphoma in HTLV-1 bZIP
    factor and Tax double transgenic mice. Archives of Virology. 159(7):1849-56, doi:
    10.1007/s00705-014-2099-y, 2014.

2013

  • Sato K, Misawa N, Iwami S, Satou Y, Matsuoka M, Ishizaka Y, Ito M, Aihara
    K, Dong Sung An and Koyanagi Y. HIV-1 Vpr accelerates viral replication during acute infection by
    exploitation of proliferating CD4+ T cells in vivo. PLoS Pathogens,
    9(12):e1003812, doi: 10.1371/journal.ppat.1003812, 2013.
  • Yamamoto-Taguchi N, Satou Y, Miyazato P, Ohshima K, Nakagawa M, Katagiri K,
    Kinashi T, Matsuoka M. HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.
    PLoS Pathog., 9(9):e1003630, doi: 10.1371/journal.ppat.1003630, 2013.
  • Satou Y, Matsuoka M. Virological and immunological mechanisms in the
    pathogenesis of human T-cell leukemia virus type 1.Reviews in Medical Virology,
    10:885, doi: 10.3389/fmicb.2019.00885, 2013.

2012

  • Satou Y, Utsunomiya A, Tanabe J, Nakagawa M, Nosaka K, Matsuoka M. HTLV-1
    modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals.
    Retrovirology, 9:46, doi: 10.1186/1742-4690-9-46, 2012.
  • Sugata K, Satou Y, Yasunaga J, Hara H, Ohshima K, Utsunomiya A, Mitsuyama
    M, and Matsuoka M. HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1
    cytokines, Blood, 119(2):434-44, doi: 10.1182/blood-2011-05-357459, 2012.
  • Satou Y, Matsuoka M. Molecular and cellular mechanism of leukemogenesis of
    ATL; emergent evidence of significant role of HBZ in HTLV-1-induced pathogenesis. Leukemia
    Research and Treatment    , 2012:213653, doi: 10.1155/2012/213653, 2012.

2011

  • Zhao T, Satou Y, Sugata K, Miyazato P, Green PL, Imamura T, and Matsuoka M.
    HTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator. Blood, 118:
    118(7):1865-76, doi: 10.1182/blood-2010-12-326199, 2011.
  • Shimizu-Kohno K, Satou Y, Arakawa F, Kiyasu J, Kimura Y, Niino D, Sugita Y,
    Ishikawa F, Matsuoka M, Ohshima K. Detection of human T-cell leukemia virus type 1 by means of HBZ in situ
    hybridization in formalin-fixed and paraffin-embedded tissues. Cancer Science,
    102(7):1432-6, doi: 10.1111/j.1349-7006.2011.01946.x, 2011.
  • Sato K, Misawa N, Nie C, Satou Y, Iwakiri D, Matsuoka M, Takahashi R,
    Kuzushima K, Ito M, Takada K, and Koyanagi Y. A novel animal model of Epstein-Barr virus-associated
    hemophagocytic lymphohistiocytosis in humanized mice. Blood, 117(21):5663-73, doi:
    10.1182/blood-2010-09-305979, 2011.
  • Hagiya K, Yasunaga J, Satou Y, Oshima K and Matsuoka M. ATF3, an HTLV-1
    bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells.
    Retrovirology, 8:19, doi: 10.1186/1742-4690-8-19, 2011.
  • Satou Y, Yasunaga J, Zhao T, Yoshida M, Miyazato
    P    , Takai K, Shimizu K, Ohshima K, Green P, Ohkura N, Yamaguchi T, Ono M, Sakaguchi S, Matsuoka M,
    HTLV-1 bZIP Factor Induces T-cell Lymphoma and Systemic Inflammation In Vivo.PLoS
    Pathogens    , 7(2):e1001274, doi: 10.1371/journal.ppat.1001274, 2011.

~2010

  • Satou Y and Matsuoka M. HTLV-1 and the host immune system: How the virus
    disrupts immune regulation, leading to HTLV-1 associated diseases. Journal of Clinical and
    Experimental Hematopathology    , 50(1):1-8, doi: 10.3960/jslrt.50.1, 2010.
  • Fan J, Ma G, Nosaka K, Tanabe J, Satou Y, Koito A, Wain-Hobson S, Vartanian
    JP, Matsuoka M. APOBEC3G Generates Nonsense Mutations in HTLV-1 Proviral Genomes In Vivo.
    Journal of Virology, 84(14):7278-87, doi: 10.1128/JVI.02239-09, 2010.
  • Saito M, Matsuzaki T, Satou Y, Yasunaga J, Saito K, Arimura K, Matsuoka M,
    Ohara Y. In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers
    and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
    Retrovirology, 6:19, doi: 10.1186/1742-4690-6-19, 2009.
  • Zhao T, Yasunaga J, Satou Y, Nakao M, Takahashi M, Fujii M, Matsuoka M.
    Human T-cell Leukemia virus type 1 bZIP factor selectively suppresses classical pathway of NF-kB.
    Blood, 113(12):2755-64, doi: 10.1182/blood-2008-06-161729, 2009.
  • Yoshida M, Satou Y, Yasunaga JI, Fujisawa JI, Matsuoka M. Transcriptional
    control of spliced and unspliced HTLV-1 bZIP factor gene. Journal of Virology,
    86(2):107-12, doi: 10.1532/IJH97.07103, 2008.
  • Satou Y, Matsuoka M. Implication of the HTLV-I bZIP Factor Gene in the
    Leukemogenesis of Adult T-Cell Leukemia. International Journal of hematology,
    107-12, doi: 10.1532/IJH97.07103, 2007.
  • Satou Y, Yasunaga JI, Yoshida M, Matsuoka M. HTLV- I bZIP factor gene mRNA
    supports proliferation of adult T-cell leukemia cells. Proceedings of the National Academy of
    Sciences of the United States of America    , 113(12):2755-64, doi:
    10.1182/blood-2008-06-161729, 2006.
  • Doi K, Wu X, Taniguchi Y, Yasunaga JI, Satou Y, Okayama A, Nosaka K,
    Matsuoka M. Preferential selection of human T-cell leukemia virus type I provirus integration sites in
    leukemic versus carrier states. Blood, 106(3):1048-5, doi:
    10.1182/blood-2004-11-4350, 2005.
  • Yasunaga JI, Taniguchi Y, Nosaka K, Yoshida M, Satou Y, Sakai T, Mitsuya H,
    Matsuoka M. Identification of aberrantly methylated genes in association with adult T-cell leukemia.
    Cancer Research, 64(17):6002-9, doi: 10.1158/0008-5472.CAN-04-1422, 2004.
  • Satou Y, Nosaka K, Koya Y, Yasunaga JI, Toyokuni S, Matsuoka M. Proteasome
    inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro.
    Leukemia, 18(8):1357-63, doi: 10.1038/sj.leu.2403400, 2004.